If we were giving one dose of COVID vaccine to every adult, instead of the two "required" for the Pfizer and Moderna vaccines, we'd have enough vaccine for every adult in the US by the end of March. By the end of this month!
Instead, we've got to wait until the end of July, because we're making the mistake of giving two doses when these vaccines are effective after only one dose.
A big part of the problem is that these vaccines were tested as two-dose regimens, so the Science supports using them as two-dose regimens, and by the time we have enough convincing evidence that one dose is enough, it won't matter.
But it's a four-month difference in ending this pandemic.
We'd be done by the end of this month if we'd tested these vaccines as one-dose regimens.
Sure, two doses, separated by 3-4 weeks, are more effective than one dose. This would be true of just about every vaccine we give, including the annual flu shot -- if you got two flu shots each winter, separated by 3-4 weeks, they'd be more effective than the one shot we get. Repeated exposure to a pathogen causes a more robust immune response, just as repeated exercise builds strength and endurance, just as studying repeatedly for a test improves your grades.
But in an emergency, as an average of 2,000 people die each day, one shot would've been enough. And then after everybody had received their first shot, we could've offered second shots.
We could've ended this pandemic this month. But instead we'll wait until the end of July. We could've saved 100,000 of the people who will die this spring and summer.
That pandemic fatigue we're all feeling -- it could've been over by the end of this month.
Instead, we've got to wait until the end of July, because we're making the mistake of giving two doses when these vaccines are effective after only one dose.
A big part of the problem is that these vaccines were tested as two-dose regimens, so the Science supports using them as two-dose regimens, and by the time we have enough convincing evidence that one dose is enough, it won't matter.
But it's a four-month difference in ending this pandemic.
We'd be done by the end of this month if we'd tested these vaccines as one-dose regimens.
Sure, two doses, separated by 3-4 weeks, are more effective than one dose. This would be true of just about every vaccine we give, including the annual flu shot -- if you got two flu shots each winter, separated by 3-4 weeks, they'd be more effective than the one shot we get. Repeated exposure to a pathogen causes a more robust immune response, just as repeated exercise builds strength and endurance, just as studying repeatedly for a test improves your grades.
But in an emergency, as an average of 2,000 people die each day, one shot would've been enough. And then after everybody had received their first shot, we could've offered second shots.
We could've ended this pandemic this month. But instead we'll wait until the end of July. We could've saved 100,000 of the people who will die this spring and summer.
That pandemic fatigue we're all feeling -- it could've been over by the end of this month.